Prostate Cancer Mortality Rate is High in Obese Men

A U.S. study published in the December 15, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society found that obese men who were diagnosed with prostate cancer are at greater risk of death after treatment.

The study was lead by Dr. Efstathiou of Massachusetts General Hospital in Boston. The study was made on 788 patients with locally advanced prostate cancer for more than eight years to find out of any specific link between BMI and high mortality rates in prostate cancer patients.

Result of the study:

  • The study found that the main risk factor of prostate cancer death at the time of treatment was Body Mass Index (BMI).
  • The study found that obese men with BMI greater than 25 kg/m2 were at double risk of dyeing from locally advanced prostate cancer than obese men with normal BMI at the time of diagnosis.
  • Dr. Efstathiou and his colleagues reported that their data supported population-based studies that report similar associations between obesity and disease-related mortality. Dr. Efstathiou concluded that, “Further studies are warranted to evaluate the mechanisms for this increased cancer-specific mortality among overweight and obese men and to assess the impact of BMI on survival following other management strategies and in clinically localized disease. Whether weight loss after prostate cancer diagnosis alters disease course remains to be determined.”

    What Cancers can Obesity Lead for Men?

    Obese men have higher risk of risk of developing cancers when compared to non-obese men. Along with prostate cancer, obese men are at risk of developing colon cancer and rectum cancer. Hence, it is very important for men to lose weight to ensure their health.


    Comorbidity, body mass index, and age and the risk of nonprostate-cancer-specific mortality after a postradiation prostate-specific antigen recurrence.

    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women’s Hospital, Boston, Massachusetts 02115, USA.pnguyen@LROC.harvard.edu

    Obesity and Weight Gain Linked to Prostate Cancer Mortality

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