Obesity Affects Your Kidney

Obesity is a frequent and dangerous condition that can damage your kidney. To learn more about the strong relationship between kidney and obesity, read on.

According to researchers at the University of California, San Francisco ( UCSF ), there is a sturdy connection between being obese and developing end-stage renal disease, or kidney failure. Basically, people who are obese or overweight are at much higher risk of kidney failure.

Here are some important facts related to kidney and obesity.

  • Research studies found that an obese person is approximately seven times more susceptible to kidney failure than normal weight people. Studies have also recommended that obesity should be considered a risk factor for the condition, and that kidney failure is yet another consequence of obesity.
  • Research findings showed that being even moderately overweight nearly doubles the risk of developing the condition, which is a complete failure of the kidneys to process waste so that dialysis or transplantation become necessary.
  • Obesity places more metabolic demand on the kidneys, forcing them to work harder. As the person gets bigger, hyper-filtration occurs and this over filtration is what tears the kidneys down.
  • Obese patients tend to develop microalbuminuria — small amounts of the protein albumin in urine. This is the first sign of diabetic kidney disease. The risk of microalbuminuria was 4.5 percent for patients who received intensive insulin therapy and 12.8 percent for those who received standard insulin treatment.
  • Studies found that the larger a patient’s waist measurement, the greater their risk for kidney disease. For each four-inch increase in waist circumference, there was a 34 percent increased risk of microalbuminuria.
  • Since the adipocyte (fat cell) is considered a source of many hormones and cytokines(kind of proteins), obesity has much more direct influences on renal function besides mediating hypertension: It can by itself induce renal disease such as focal segmental glomerulosclerosis, but also, more commonly, bring about progression of chronic renal diseases.